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Article

Disease Mutation Study Identifies Critical Residues for Phosphatidylserine Flippase ATP11A.

BioMed research international - 1 Jan 2020

Sun Kuanxiang, Tian Wanli, Li Xiao, Liu Wenjing, Yang Yeming, Zhu Xianjun

Abstract excerpt

Phosphatidylserine flippase (P4-ATPase) transports PS from the outer to the inner leaflet of the lipid bilayer in the membrane to maintain PS asymmetry, which is important for biological activities of the cell. ATP11A is expressed in multiple tissues and plays a role in myotube formation. However, the detailed cellular function of ATP11A remains elusive. Mutation analysis revealed that I91, L308, and E897...

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Identifiers

PMID: 32596364
DOI: 10.1155/2020/7342817
PMCID: PMC7288202

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Source receipt: pubmed, retrieved 7 Sept 2026.

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