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Structural Determinants for the Monomeric and Phospholipid-Transport P4B-ATPase via comprehensive <i>in silico</i> analysis of P4-ATPase structures

2025-07-04

Abstract excerpt

<h4>ABSTRACT</h4> The P4-ATPase family of phospholipid flippases plays a critical role in maintenance of membrane asymmetry and cellular protein traffic and eukaryotic homeostasis. Several structures of these phospholipid flippases have been resolved, along with extensive biochemical characterization of the substrate transport properties. However, an essential subfamily of monomeric phospholipid flippases, the P4...

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Literature Corpus work
abfb7e60-76c0-509b-b6f8-2d9aa8493bc0
DOI
10.1101/2025.07.01.662597
Open publication

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Structural Determinants for the Monomeric and Phospholipid-Transport P4B-ATPase via comprehensive <i>in silico</i> analysis of P4-ATPase structuresDOI 10.1101/2025.07.01.662597
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