Article

Does a common genetic event exist for familial thyroid cancer? Results from a large family with FNMTC

2024-01-03

Abstract excerpt

<h4>Background: </h4> Despite several efforts, the genetic susceptibility of familial non medullary thyroid cancer (FNMTC), has remained still elusive. Methods We performed Whole Exome Sequencing (WES) in a large family with 9 available members, 6/9 (67%) affected by FNMTC. Results We found two missense variants, with CADD score > 20: the c.C1519A (p.Pro507Thr, rs773271544) in PRKCɛ gene and the c.G1019A (p.R340...

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Literature Corpus work: f7c3bf5d-8db0-53d9-b9bf-5a926e303e50
DOI: 10.21203/rs.3.rs-3822232/v1

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