Article
Novel Susceptibility Genes Drive Familial Non-Medullary Thyroid Cancer in a Large Consanguineous Kindred.
International journal of molecular sciences - 4 May 2023
Majdalani Pierre, Yoel Uri, Nasasra Tayseer, Fraenkel Merav, Haim Alon, Loewenthal Neta, Zarivach Raz, Hershkovitz Eli, Parvari Ruti
Abstract excerpt
Familial non-medullary thyroid cancer (FNMTC) is a well-differentiated thyroid cancer (DTC) of follicular cell origin in two or more first-degree relatives. Patients typically demonstrate an autosomal dominant inheritance pattern with incomplete penetrance. While known genes and chromosomal loci account for some FNMTC, the molecular basis for most FNMTC remains elusive. To identify the variation(s) causing FNMTC...
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