Article
Identification of susceptibility gene mutations associated with the pathogenesis of familial nonmedullary thyroid cancer.
Molecular genetics & genomic medicine - 1 Dec 2019
Zhu Junwei, Wu Kaile, Lin Zhangying, Bai Suwen, Wu Jing, Li Peikun, Xue Haowei, Du Juan, Shen Bing, Wang Huiyin, Liu Yehai
Abstract excerpt
BACKGROUND: Familial nonmedullary thyroid cancer (FNMTC) accounts for approximately 3%-9% of all thyroid cancers; however, the mechanisms underlying FNMTC remain unclear. Environmental and genetic (especially genetic mutation) factors may play important roles in FNMTC etiology, development, and pathogenesis. METHODS: Three affected members, including two first-degree relatives, and three healthy members of a...
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