Article

<i>cfrB, cfrC</i> , and a potential new <i>cfr</i> -like gene in <i>Clostridium difficile</i> strains recovered across Latin America

2019-05-24

Abstract excerpt

<h4>ABSTRACT</h4> Cfr is a radical S -adenosyl-L-methionine (SAM) enzyme that confers cross-resistance to all antibiotics targeting the large ribosomal subunit through hypermethylation of nucleotide A2503 of 23S rRNA. Of the four known cfr genes known to date, cfr (B) and cfr (C) have been sporadically found in C. difficile , yet functional characterization of cfr (C) is still lacking. We identified genes f...

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Literature Corpus work: f7b9f85b-9232-5557-87ff-0cfe60283fb2
DOI: 10.1101/649020

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