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Phosphatidylinositol 4,5-bisphosphate regulates cilium transition zone maturation in <i>Drosophila melanogaster</i>

2018-05-05

Abstract excerpt

Cilia are cellular antennae that are essential for human development and physiology. A large number of genetic disorders linked to cilium dysfunction are associated with proteins that localize to the ciliary transition zone (TZ), a structure at the base of cilia that regulates trafficking in and out of the cilium. Despite substantial effort to identify TZ proteins and their roles in cilium assembly and function, p...

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Literature Corpus work
dd54a12b-f5d6-5f54-9fe9-217092dc0b2d
DOI
10.1101/315275
Open publication

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Phosphatidylinositol 4,5-bisphosphate regulates cilium transition zone maturation in <i>Drosophila melanogaster</i>DOI 10.1101/315275
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