Article
Endocytosis genes facilitate protein and membrane transport in C. elegans sensory cilia.
Current biology : CB - 20 Mar 2012
Kaplan Oktay I, Doroquez David B, Cevik Sebiha, Bowie Rachel V, Clarke Lara, Sanders Anna A W M, Kida Katarzyna, Rappoport Joshua Z, Sengupta Piali, Blacque Oliver E
Abstract excerpt
BACKGROUND: Multiple intracellular transport pathways drive the formation, maintenance, and function of cilia, a compartmentalized organelle associated with motility, chemo-/mechano-/photosensation, and developmental signaling. These pathways include cilium-based intraflagellar transport (IFT) and poorly understood membrane trafficking events. Defects in ciliary transport contribute to the etiology of human...
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