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VEGFA-Positive Macrophages Regulate Aqueous Humor Outflow in Aged Mice and Humans

2026-08-24

Abstract excerpt

Elevated intraocular pressure (IOP) and aging are major risk factors for primary open-angle glaucoma (POAG), but how aging affects IOP regulation remains poorly understood. IOP remains within a narrow range despite age-associated changes predicted to increase aqueous humor outflow (AHO) resistance at the interface between the trabecular meshwork and Schlemm's canal (SC), suggesting compensatory mechanisms preserve...

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Literature Corpus work
f7ab6dfe-1d3e-5e68-bd7a-d45ec8be4ce7
DOI
10.64898/2026.08.20.746006
Open publication

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VEGFA-Positive Macrophages Regulate Aqueous Humor Outflow in Aged Mice and HumansDOI 10.64898/2026.08.20.746006
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