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Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell states

2023-09-03

Abstract excerpt

Schlemm’s canal (SC) is central in intraocular pressure regulation but requires much characterization. It has distinct inner and outer walls, each composed of Schlemm’s canal endothelial cells (SECs) with different morphologies and functions. Recent transcriptomic studies of the anterior segment added important knowledge, but were limited in power by SEC numbers or did not focus on SC. To gain a more comprehensive...

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Literature Corpus work
a0b27d1f-b89f-5997-a353-ab8cc09bfec6
DOI
10.1101/2023.08.31.555823
Open publication

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Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell statesDOI 10.1101/2023.08.31.555823
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