Article
Cell Atlas of Aqueous Humor Outflow Pathways in Eyes of Humans and Four Model Species Provides Insights into Glaucoma Pathogenesis
2020-02-04
Abstract excerpt
<h4>ABSTRACT</h4> Increased intraocular pressure (IOP) represents a major risk factor for glaucoma, a prevalent eye disease characterized by death of retinal ganglion cells that carry information from the eye to the brain; lowering IOP is the only proven treatment strategy to delay disease progression. The main determinant of IOP is the equilibrium between production and drainage of aqueous humor, with compromise...
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Identifiers and source
- Literature Corpus work
- c0391bd7-bdec-5629-a460-9041a56fe623
- DOI
- 10.1101/2020.02.04.933911
