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Article

Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues

8 Jan 2024

Abstract excerpt

The progressive degradation in the trabecular meshwork (TM) is related to age-related ocular diseases like primary open-angle glaucoma. However, the molecular basis and biological significance of the aging process in TM have not been fully elucidated. Here, we established a dynamic single-cell transcriptomic landscape of aged macaque TM, wherein we classified the outflow tissue into 12 cell subtypes and...

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PMID: 38366188
DOI: 10.1093/procel/pwad067

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