Article

Targeting of a novel interplay between MET Tyrosine Kinase and NRF2 enhances sensitivity to Paclitaxel in Triple Negative Breast Cancer

2025-06-16

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Triple-negative breast cancer (TNBC) is a very aggressive and heterogeneous cancer. The lack of effective targeted therapies and frequency of relapse point to the urgent need for identifying molecular vulnerabilities to overcome resistance to chemotherapy. Nuclear Factor Erythroid 2-related factor 2 (NRF2) is a transcription factor that plays a central role in...

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Literature Corpus work: f7ab4ad1-b6c9-5a07-a992-7c1d2f205a97
DOI: 10.21203/rs.3.rs-6855159/v1

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