Article
Triple negative breast cancer: looking for the missing link between biology and treatments.
Oncotarget - 29 Sept 2015
Palma Giuseppe, Frasci Giuseppe, Chirico Andrea, Esposito Emanuela, Siani Claudio, Saturnino Carmela, Arra Claudio, Ciliberto Gennaro, Giordano Antonio, D'Aiuto Massimiliano
Abstract excerpt
The so called "Triple Negative Breast Cancer" (TNBC) represents approximately 15-20% of breast cancers. This acronym simply means that the tumour does not express oestrogen receptor (ER) and progesterone receptor (PR) and does not exhibit amplification of the human epidermal growth factor receptor 2 (HER2) gene. Despite this unambiguous definition, TNBCs are an heterogeneous group of tumours with just one common...
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