Article

Crosstalk between YAP and HER2 drives HER2-mediated breast cancer progression via synergistic growth factor upregulation

2025-09-24

Abstract excerpt

<title>Abstract</title> <p>Breast cancer is the most frequently diagnosed cancer worldwide, with the HER2-positive subtype accounting for ~ 25% of cases. In this study, we examine the role of oncogene YAP in HER2-positive breast cancer progression and YAP as a potential therapeutic target in combination with HER2-targeted therapy. We studied expression of YAP in 76 HER2-positive patients, high expression of YAP w...

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Literature Corpus work: 4f8ecad8-a552-5267-a4a0-ab7b7d661868
DOI: 10.21203/rs.3.rs-7499611/v1

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