Article

NRF2 activation by cysteine as a survival mechanism for triple-negative breast cancer cells

2024-01-15

Abstract excerpt

<title>Abstract</title> <p>Triple-negative breast cancer (TNBC) is a very aggressive and heterogeneous group of tumors. In order to develop effective therapeutic strategies, it is therefore essential to identify the subtype-specific molecular mechanisms underlying disease progression and resistance to chemotherapy. TNBC cells are highly dependent on exogenous cystine, provided by overexpression of the cystine/glu...

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Literature Corpus work: 53b464bd-4739-5ac9-b7a7-a91de48c2b1f
DOI: 10.21203/rs.3.rs-3849836/v1

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