Article

FUS modulates the level of ribosomal RNA modifications by regulating a subset of snoRNA expression

2022-11-09

Abstract excerpt

<h4>ABSTRACT</h4> FUS is a multifunctional protein involved in many aspects of RNA metabolism, including transcription, splicing, translation, miRNA processing, and replication-dependent histone gene expression. In this paper, we show that FUS depletion results in differential expression of numerous small nucleolar RNAs (snoRNAs) that guide 2’-O methylation (2’-O-Me) and pseudouridylation of specific positions in...

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Literature Corpus work: f7ab07bb-432b-59b7-938a-3768178fee74
DOI: 10.1101/2022.11.09.515592

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