Article

Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals

2020-09-04

Abstract excerpt

<h4>ABSTRACT</h4> Chronic kidney disease (CKD) has a complex genetic underpinning. Genome-wide association studies (GWAS) of CKD-defining glomerular filtration rate (GFR) have identified hundreds of loci, but prioritization of variants and genes is challenging. To expand and refine GWAS discovery, we meta-analyzed GWAS data for creatinine-based estimated GFR (eGFRcrea) from the Chronic Kidney Disease Genetics Con...

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Literature Corpus work: f77d9120-4773-5d51-92bf-793ab169cdb4
DOI: 10.1101/2020.09.04.283713

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