Article
KidneyGPS: a user-friendly web application to help prioritize kidney function genes and variants based on evidence from genome-wide association studies.
BMC bioinformatics - 21 Sept 2023
Stanzick Kira J, Stark Klaus J, Gorski Mathias, Schödel Johannes, Krüger René, Kronenberg Florian, Warth Richard, Heid Iris M, Winkler Thomas W
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified hundreds of genetic loci associated with kidney function. By combining these findings with post-GWAS information (e.g., statistical fine-mapping to identify independent association signals and to narrow down signals to causal variants; or different sources of annotation data), new hypotheses regarding physiology and disease aetiology can be...
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