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Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

23 Apr 2019

Abstract excerpt

Chronic kidney disease (CKD) is a growing health burden currently affecting 10-15% of adults worldwide. Estimated glomerular filtration rate (eGFR) as a marker of kidney function is commonly used to diagnose CKD. We analyze eGFR data from the Nord-Trøndelag Health Study and Michigan Genomics Initiative and perform a GWAS meta-analysis with public summary statistics, more than doubling the sample size of previous...

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PMID: 31015462
DOI: 10.1038/s41467-019-09861-z

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