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Distinctive patterns of DNA methylation associated with Parkinson disease

16 Aug 2013

Abstract excerpt

Parkinson disease (PD) is a multifactorial neurodegenerative disorder with high incidence in the elderly, where environmental and genetic factors are involved in etiology. In addition, epigenetic mechanisms, including deregulation of DNA methylation have been recently associated to PD. As accurate diagnosis cannot be achieved pre-mortem, identification of early pathological changes is crucial to enable...

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PMID: 23907097
DOI: 10.4161/epi.25865

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