Article

BANDITS: Bayesian differential splicing accounting for sample-to-sample variability and mapping uncertainty

2019-08-29

Abstract excerpt

Alternative splicing is a biological process during gene expression that allows a single gene to code for multiple proteins. However, splicing patterns can be altered in some conditions or diseases. Here, we present BANDITS, a R/Bioconductor package to perform differential splicing, at both gene and transcript-level, based on RNA-seq data. BANDITS uses a Bayesian hierarchical structure to explicitly model the vari...

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Literature Corpus work: f75f106f-9767-580a-93ff-f3f49e122b50
DOI: 10.1101/750018

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