Article

Comprehensive and scalable quantification of splicing differences with MntJULiP

2020-10-27

Abstract excerpt

Alternative splicing of mRNA is an essential gene regulatory mechanism with important roles in development and disease. We present MntJULiP, a method for comprehensive and accurate quantification of splicing differences between two or more conditions. MntJULiP implements novel Dirichlet-multinomial and zero-inflated negative binomial models within a Bayesian framework to detect both changes in splicing ratios and...

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Literature Corpus work: 4d759736-d737-5f7b-a81a-11421a730a4f
DOI: 10.1101/2020.10.26.355941

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