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Article

Profiling genetically driven alternative splicing across the Indonesian archipelago.

American journal of human genetics - 7 Nov 2024

Ibeh Neke, Kusuma Pradiptajati, Crenna Darusallam Chelzie, Malik Safarina G, Sudoyo Herawati, McCarthy Davis J, Gallego Romero Irene

Abstract excerpt

One of the regulatory mechanisms influencing the functional capacity of genes is alternative splicing (AS). Previous studies exploring the splicing landscape of human tissues have shown that AS has contributed to human biology, especially in disease progression and the immune response. Nonetheless, this phenomenon remains poorly characterized across human populations, and it is unclear how genetic and...

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Identifiers

PMID: 39383868
DOI: 10.1016/j.ajhg.2024.09.004
PMCID: PMC11568790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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