Article

An exactly solvable, spatial model of mutation accumulation in cancer

2016-10-27

Abstract excerpt

One of the hallmarks of cancer is the accumulation of driver mutations which increase the net reproductive rate of cancer cells and allow them to spread. This process has been studied in mathematical models of well mixed populations, and in computer simulations of three-dimensional spatial models. But the computational complexity of these more realistic, spatial models makes it difficult to simulate realistically...

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Identifiers and source

Literature Corpus work: f73da816-4d72-585f-9f2f-519712ca847e
DOI: 10.1101/084038

Open publication

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