Article
The linear process of somatic evolution.
Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 2003
Nowak Martin A, Michor Franziska, Iwasa Yoh
Abstract excerpt
Cancer is the consequence of an unwanted evolutionary process. Cells receive mutations that alter their phenotype. Especially dangerous are those mutations that increase the net reproductive rate of cells, thereby leading to neoplasia and later to cancer. The standard models of evolutionary dynam...
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