Article

In vivo cross-linking and transmembrane helix dynamics support a bidirectional non-piston model of signaling within E. coli EnvZ

2017-10-20

Abstract excerpt

In Gram-negative bacteria, porins span the outer membrane and control the influx of several prominent groups of antibiotics. Thus, it should not be surprising that expression of these porins is often altered in clinical isolates exhibiting multidrug resistance (MDR). The major regulator of porin expression in Escherichia coli is EnvZ, a canonical sensor histidine kinase (SHK). It allosterically processes periplas...

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Literature Corpus work: f6e7aa3d-dd24-56da-be68-ea6f059421b1
DOI: 10.1101/206888

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<i>In vivo</i> cross-linking and transmembrane helix dynamics support a bidirectional non-piston model of signaling within <i>E. coli</i> EnvZ

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