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Article

The inner membrane histidine kinase EnvZ senses osmolality via helix-coil transitions in the cytoplasm.

The EMBO journal - 30 May 2012

Wang Loo Chien, Morgan Leslie K, Godakumbura Pahan, Kenney Linda J, Anand Ganesh S

Abstract excerpt

Two-component systems mediate bacterial signal transduction, employing a membrane sensor kinase and a cytoplasmic response regulator (RR). Environmental sensing is typically coupled to gene regulation. Understanding how input stimuli activate kinase autophosphorylation remains obscure. The EnvZ/OmpR system regulates expression of outer membrane proteins in response to osmotic stress. To identify EnvZ...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22543870
DOI: 10.1038/emboj.2012.99
PMCID: PMC3365433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The inner membrane histidine kinase EnvZ senses osmolality via helix-coil transitions in the cytoplasm.PMID 22543870Read ↗

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