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Article

Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling.

PLoS computational biology - 1 Oct 2011

Hall Benjamin A, Armitage Judith P, Sansom Mark S P

Abstract excerpt

Transmembrane α-helices play a key role in many receptors, transmitting a signal from one side to the other of the lipid bilayer membrane. Bacterial chemoreceptors are one of the best studied such systems, with a wealth of biophysical and mutational data indicating a key role for the TM2 helix in signalling. In particular, aromatic (Trp and Tyr) and basic (Arg) residues help to lock α-helices into a membrane....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22028633
DOI: 10.1371/journal.pcbi.1002204
PMCID: PMC3197627

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Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling.PMID 22028633Read ↗

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