Article

<i>In situ</i> NMR reveals a pH sensor motif in an outer membrane protein that drives bacterial vesicle production

2025-01-24

Abstract excerpt

The outer membrane vesicles (OMVs) produced by diderm bacteria have important roles in cell envelope homeostasis, secretion, interbacterial communication, and pathogenesis. The facultative intracellular pathogen Salmonella enterica Typhimurium (STm) activates OMV biogenesis inside the acidic vacuoles of host cells by upregulating the expression of the outer membrane (OM) protein PagC, one of the most robustly act...

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Literature Corpus work: fbd81562-e1c0-5395-8a6d-217acd937967
DOI: 10.1101/2025.01.21.634179

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