Article
Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C. elegans.
PLoS genetics - 1 May 2006
Cui Mingxue, Kim E Bridget, Han Min
Abstract excerpt
In Caenorhabditis elegans, vulval cell-fate specification involves the activities of multiple signal transduction and regulatory pathways that include a receptor tyrosine kinase/Ras/mitogen-activated protein kinase pathway and synthetic multivulva (SynMuv) pathways. Many genes in the SynMuv pathw...
Topics
- Animals
- Caenorhabditis elegans
- Cell Lineage
- Chromatin
- Gene Expression Regulation, Developmental
- Gene Silencing
- Genome
- Humans
- Models, Genetic
- Mutation
- Phenotype
- RNA Interference
- Retinoblastoma Protein
- Transgenes
