Article

Investigation of de novo mutations in a schizophrenia case-parent trio by induced pluripotent stem cell based in vitro disease-modeling: Convergence of schizophrenia and autism-related cellular phenotypes

2020-08-12

Abstract excerpt

<title>Abstract</title> <p>Background: De novo mutations (DNMs) have been implicated in the etiology of schizophrenia (SZ), a chronic debilitating psychiatric disorder characterized by hallucinations, delusions, cognitive dysfunction and decreased community functioning. Several DNMs have been identified by examining SZ cases and their unaffected parents, however in most cases the biological significance of these...

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Literature Corpus work: f6de34fd-ecaa-533d-ade0-179804ab5a79
DOI: 10.21203/rs.2.20699/v2

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