Article

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

2004-02-01

Abstract excerpt

According to the quality of response they mediate, autoreactive T cells recognizing islet beta cell peptides could represent both disease effectors in the development of type 1 diabetes (T1DM) and directors of tolerance in nondiabetic individuals or those undergoing preventative immunotherapy. A combination of the rarity of these cells, inadequate technology, and poorly defined epitopes, however, has hampered exam...

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Literature Corpus work: f6dcc2b5-3cf5-540c-bbef-308138fa1ff0
DOI: 10.1172/jci200419585

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