Article
Prediction and pathogenesis in type 1 diabetes.
Immunity - 23 Apr 2010
Ziegler Anette-G, Nepom Gerald T
Abstract excerpt
A combination of genetic and immunological features is useful for prediction of autoimmune diabetes. Patterns of immune response correspond to the progression from a preclinical phase of disease to end-stage islet damage, with biomarkers indicating transition from susceptibility to active autoimmunity, and to a final loss of immune regulation. Here, we review the markers that provide evidence for immunological...
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