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Article

Type 1 diabetes mellitus-associated genetic variants contribute to overlapping immune regulatory networks

2018-05-17

Abstract excerpt

Type 1 diabetes (T1D) is a chronic metabolic disorder characterised by the autoimmune destruction of insulin-producing pancreatic islet beta cells in genetically predisposed individuals. Genome-wide association studies (GWAS) have identified over 60 risk loci across the human genome, marked by single nucleotide polymorphisms (SNPs), which confer genetic predisposition to T1D. There is increasing evidence that dise...

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Literature Corpus work
1983e39d-116c-5382-be46-202dbe99c755
DOI
10.1101/325225
Open publication

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Type 1 diabetes mellitus-associated genetic variants contribute to overlapping immune regulatory networksDOI 10.1101/325225
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