Article
In silico analysis reveals interrelation of enriched pathways and genes in type 1 diabetes.
Immunogenetics - 1 Oct 2020
Sur Saubashya
Abstract excerpt
Type 1 diabetes (T1D) is a multifactorial, polygenic complex autoimmune disease damaging pancreatic islet β cells. Numerous genes linked to T1D have been discovered through genetical studies, GWAS and polymorphisms. Most genetical studies focused on independent genes while others overemphasized on SNPs. Here, a collective analysis of documented T1D-associated genes was performed using bioinformatics tools....
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