Article

An epigenetic mechanism of azole tolerance facilitates acquired antifungal resistance in <i>Aspergillus fumigatus</i>

2026-03-16

Abstract excerpt

Antibiotic tolerance paves the way for acquired resistance in bacterial pathogens. However, the mechanisms of tolerance and its evolutionary role in acquired resistance in pathogenic fungi, particularly molds, remains elusive. Here, we identified an In hibitor of G rowth domain protein (IngB) as a novel epigenetic regulator of azole tolerance in Aspergillus fumigatus . The loss of ingB promotes supra-MIC growt...

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Literature Corpus work: f69d6550-5c20-5590-912c-deac4955f684
DOI: 10.64898/2026.03.16.712083

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