Article

<i>In silico</i> Computed Clusters of Prostate Luminal Progenitors Match FACS-Enriched LSC <sup>med</sup> cells

2021-06-17

Abstract excerpt

Several groups recently published single-cell (sc) expression atlases of the adult mouse prostate cells based on RNA sequencing (scRNA-seq) data. All studies identified one computerized cluster of non-secretory luminal progenitor cells enriched in luminal and stemness-related gene transcripts. The actual correspondence between these luminal progenitor cell clusters has not been investigated. In addition, the prese...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f65eac3d-640c-59a6-8a62-494e0871d324
DOI: 10.1101/2021.06.16.448624

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>In silico</i> Computed Clusters of Prostate Luminal Progenitors Match FACS-Enriched LSC <sup>med</sup> cellsDOI 10.1101/2021.06.16.448624Read

Cellular cartography reveals mouse prostate organization and determinants of castration resistanceSemantic proximity Read

Identification of a basal stem cell subpopulation in the prostate via functional, lineage tracing and single-cell RNA-seq analysesSemantic proximity Read

Multilineage plasticity in prostate cancer through expansion of stem–like luminal epithelial cells with elevated inflammatory signalingSemantic proximity Read

Cellular cartography reveals mouse prostate organization and determinants of castration resistanceSemantic proximity Read

Intermediate basal cell population in prostate homeostasis and cancer initiationSemantic proximity Read

Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancerSemantic proximity Read

A luminal intermediate cell state maintains long-term prostate homeostasis and contributes to tumorigenesisSemantic proximity Read

Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors.Semantic proximity Read

The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1Semantic proximity Read

Unveiling novel double-negative prostate cancer subtypes through single-cell RNA sequencing analysisSemantic proximity Read

A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours.Semantic proximity Read

Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancerSemantic proximity Read