Article

Reprogramming of Energy Metabolism in Human <em>PKD1</em> Polycystic Kidney Disease: A Systems Biology Analysis

2024-05-10

Abstract excerpt

(1) Background: Multiple alterations of cellular metabolism have been documented in experimental studies of autosomal dominant polycystic kidney disease (ADPKD) and are thought to contribute to its pathogenesis. (2) Methods: To elucidate the molecular pathways and transcriptional regulators associated with the metabolic changes of renal cysts in ADPKD, we compared global gene expression data from human PKD1 renal...

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Literature Corpus work: f6391bc1-6779-5311-a622-a8f4da670834
DOI: 10.20944/preprints202405.0678.v1

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