Article

<i>Pkd1</i> mutation has no apparent effects on peroxisome structure or lipid metabolism

2021-02-09

Abstract excerpt

<h4>Background</h4> Multiple studies of tissue and cell samples from patients and pre-clinical models of autosomal dominant polycystic kidney disease report abnormal mitochondrial function and morphology and suggest metabolic reprogramming is an intrinsic feature of this disease. Peroxisomes interact with mitochondria physically and functionally, and congenital peroxisome biogenesis disorders can cause various ph...

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Literature Corpus work: 597fe038-4f26-5fed-9cdb-a6e2f1f7572d
DOI: 10.1101/2021.02.08.430145

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