Article

CCAFE: Estimating Case and Control Allele Frequencies from GWAS Summary Statistics

2024-10-29

Abstract excerpt

Methods involving summary statistics in genetics can be quite powerful but can be limited in utility. For instance, many post-hoc analyses of disease studies require case and control allele frequencies (AFs), which are not always published. We present two frameworks to derive case and control AFs from GWAS summary statistics using the odds ratio, case and control sample sizes, and either the total (case and contro...

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Literature Corpus work: f6237e6d-6431-5346-a59c-dcd6fa6620ef
DOI: 10.1101/2024.10.24.619530

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