Article

Absence of co-occurrence between HER2 amplification and dMMR/MSI in colorectal cancer: a multicentric study

2026-04-26

Abstract excerpt

<title>Abstract</title> <p> Mismatch repair deficiency (dMMR)/Microsatellite instability (MSI) plays a central role in colorectal cancer (CRC) as a predictive and prognostic biomarker and as a “red flag” for diagnosis of Lynch Syndrome (LS). <italic>HER2</italic> is emerging as a therapeutic target and clinical trials are ongoing. Several reports suggested that <italic>HER2</italic> amplification could be mu...

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Literature Corpus work: f60a74ed-417f-5241-a0c1-e671138c9763
DOI: 10.21203/rs.3.rs-9105189/v1

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