Article

Impact of different selection approaches for identifying Lynch Syndrome-related colorectalcancer patients: unity is strength

2022-01-10

Abstract excerpt

<h4>Introduction: </h4> Lynch syndrome (LS) is an inherited genetic condition associated with increased predisposition to colorectal cancer (CRC) and other tumors and is caused by germline mutations in Mismatch Repair (MMR) or EPCAM genes. The identification of LS carriers is currently based on germline testing of subjects with MMR-deficient (dMMR) tumors or fulfilling clinical criteria, but the most efficient str...

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Literature Corpus work: 937a7aba-bd50-54f6-b24e-d5ee3f332e29
DOI: 10.32388/011cpm

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