Article
Relationship of HER2 Alteration and Microsatellite Instability Status in Colorectal Adenocarcinoma.
The oncologist - 1 Jul 2021
Qiu Miao-Zhen, He Cai-Yun, Yang Xin-Hua, Yang Li-Qiong, Lin Jun-Zhong, Zhou Da-Lei, Long Ya-Kang, Guan Wen-Long, Jin Ying, Li Yu-Hong, Wang Feng-Hua, Yang Da-Jun, Xu Rui-Hua
Abstract excerpt
BACKGROUND: The impact of HER2 somatic mutations in colorectal carcinoma (CRC) has not been well studied and its relationship with microsatellite instability-high (MSI-H) is yet to be fully elucidated. MATERIALS AND METHODS: From February 2017 to February 2020, the data of patients with CRC who underwent next-generation sequencing and had detailed record of clinicopathological information were investigated. HER2...
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