Article

Plasma proteomics reveals continuous molecular heterogeneity rather than discrete subtypes in Alzheimer’s disease

2026-07-07

Abstract excerpt

<h4>Structured Abstract</h4> <h4>INTRODUCTION</h4> Alzheimer’s disease is clinically and biologically heterogeneous. We asked whether plasma proteomics separates patients into discrete molecular subtypes or instead reflects continuous biological variation. <h4>METHODS</h4> We studied 5,895 Global Neurodegeneration Proteomics Consortium (GNPC) participants with Alzheimer’s disease or mild cognitive impairment us...

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Literature Corpus work: f5cc2d33-d1d9-5fb5-8cca-f2f00962a589
DOI: 10.64898/2026.07.04.26357296

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