Article

Deep Plasma Proteomics Reveals Shared and Disease-Specific Molecular Signatures in Alzheimer’s Disease and Frontotemporal Dementia

2026-04-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> Alzheimer’s disease (AD) and frontotemporal dementia (FTD) have considerable clinical and pathological overlap. While plasma proteomics has advanced in AD, deep comparative analyses with FTD-particularly in diverse, biomarker-confirmed Asian cohorts-remain limited. <h4>METHODS</h4> Plasma from 101 individuals with known pTau217 status was profiled using Olink Explore-HT....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ba7bf48b-b096-56a5-9e59-7dcb4f7e3e70
DOI: 10.64898/2026.04.14.26350728

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Deep Plasma Proteomics Reveals Shared and Disease-Specific Molecular Signatures in Alzheimer’s Disease and Frontotemporal DementiaDOI 10.64898/2026.04.14.26350728Read

High-sensitivity plasma proteomics reveals disease-specific signatures and predictive biomarkers of Alzheimer’s disease phenotypes in a large mixed dementia cohortSemantic proximity Read

High-sensitivity plasma proteomics reveals disease-specific signatures and predictive biomarkers of Alzheimer's disease phenotypes in a large mixed-dementia cohort.Semantic proximity Read

Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later lifeSemantic proximity Read

Proteome-wide association study identifies novel Alzheimer's disease- associated proteinsSemantic proximity Read

Identification of Novel Biomarkers for Alzheimer’s Disease and Related Dementias Using Unbiased Plasma ProteomicsSemantic proximity Read

Novel Plasma Proteins Associated With Alzheimer’s Disease Risk in APOE ε4 Carriers and Non-carriersSemantic proximity Read

Mapping the circulating proteome across neurodegeneration: A harmonized, consortium-scale framework for uncovering molecular pathophysiologySemantic proximity Read

Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer’s Disease related proteinsSemantic proximity Read

Proteomic landscape of Alzheimer’s Disease: novel insights into pathogenesis and biomarker discoverySemantic proximity Read

Cerebrospinal fluid proteomics in patients with Alzheimer’s disease reveals five molecular subtypes with distinct genetic risk profilesSemantic proximity Read

Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia riskSemantic proximity Read

Large-scale cerebrospinal fluid proteomic analysis in Alzheimer’s disease patients reveals five molecular subtypes with distinct genetic risk profilesSemantic proximity Read