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Article

Cell fate analysis of embryonic ventral mesencephalic grafts in the 6-OHDA model of Parkinson's disease.

PloS one - 1 Jan 2012

Neto Sonya Carvalho, Salti Ahmad, Puschban Zoe, Stefanova Nadia, Nat Roxana, Dechant Georg, Wenning Gregor K

Abstract excerpt

Evidence from carefully conducted open label clinical trials suggested that therapeutic benefit can be achieved by grafting fetal dopaminergic (DAergic) neurons derived from ventral mesencephalon (VM) into the denervated striatum of Parkinson's disease (PD) patients. However, two double-blind trials generated negative results reporting deleterious side effects such as prominent dyskinesias. Heterogeneous...

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Identifiers

PMID: 23209667
DOI: 10.1371/journal.pone.0050178
PMCID: PMC3510255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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