Article

Microvascular insulin resistance associates with enhanced muscle glucose disposal in CD36 deficiency.

2024-02-18

Abstract excerpt

Dysfunction of endothelial insulin delivery to muscle associates with insulin resistance. CD36, a fatty acid transporter and modulator of insulin signaling is abundant in endothelial cells, especially in capillaries. Humans with inherited 50% reduction in CD36 expression have endothelial dysfunction but whether it is associated with insulin resistance is unclear. Using hyperinsulinemic/euglycemic clamps in Cd36-/-...

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Literature Corpus work: f586f065-81fe-5d2a-96aa-29c41490bb87
DOI: 10.1101/2024.02.16.24302950

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