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Image-based deep learning reveals the responses of human motor neurons to stress and ALS

2021-04-09

Abstract excerpt

<h4>SUMMARY</h4> Although morphological attributes of cells and their substructures are recognized readouts of physiological or pathophysiological states, these have been relatively understudied in amyotrophic lateral sclerosis (ALS) research. In this study we integrate multichannel fluorescence high-content microscopy data with deep-learning imaging methods to reveal - directly from unsegmented images - novel ne...

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Literature Corpus work
149f8024-2637-56d2-83cb-22256740aa3b
DOI
10.1101/2021.04.08.439054
Open publication

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