Article

Morphology-Aware Profiling of Highly Multiplexed Tissue Images using Variational Autoencoders

2025-06-27

Abstract excerpt

<h4>ABSTRACT</h4> Spatial proteomics (highly multiplexed tissue imaging) provides unprecedented insight into the types, states, and spatial organization of cells within preserved tissue environments. To enable single-cell analysis, high-plex images are typically segmented using algorithms that assign marker signals to individual cells. However, conventional segmentation is often imprecise and susceptible to signa...

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Literature Corpus work: 680a234e-a26b-5a21-81d9-dedb7f3fcd27
DOI: 10.1101/2025.06.23.661064

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